“I believe we may extrapolate these findings to humans and anticipate that we would benefit from these combination treatments as well,” said Yao-Ping Lu, an associate research professor of chemical biology and director of skin cancer prevention at the Rutgers Ernest Mario School of Pharmacy in Piscataway, New Jersey, who presented the findings on Tuesday at the annual American Association for Cancer Research. He believes the key to the cancer fighting combo is that overall, it reduces inflammation.
And even those of you who’d just as soon imbibe your caffeinated beverages without getting up from the couch can take comfort in the findings. Caffeine alone reduced tumors by 27 percent and tumor size by 61 percent. Also exciting is the fact that these mice lost weight despite being fed a high-fat diet. The rodents’ “parametrial fat pad” weight decreased by 30 percent without exercise.
Mice that exercised but didn’t have caffeine saw 35 percent fewer tumors and 40 percent smaller ones. They also reduced their fat pad by 63 percent.